A breakthrough in early cancer detection
Our technology is supported by evidence from our population-scale clinical study program, believed to be the largest of its kind.
Clinical studies
REACH/Galleri-Medicare Study
This multi-center comparative, prospective, cohort study is designed to assess the real world clinical impact, including safety and test performance, of the Galleri® test.
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PATHFINDER 2 Study
This is a prospective, multi-center interventional study of the Galleri® multi-cancer early detection test with return of test results for participants enrolled through healthcare systems in North America.
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REFLECTION Study
An observational study of patients who have been administered the Galleri® test.
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NHS-Galleri Trial
A prospective, randomized, controlled trial to assess the performance and clinical utility of the Galleri® test for population screening in the UK when added to standard of care.
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SUMMIT Study
A prospective, observational, longitudinal, cohort study in London, United Kingdom. The study is designed to enroll approximately 13,000 men and women who do not have a high risk for lung or other cancer due to significant smoking history at the time of enrollment.
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STRIVE Study
A prospective, observational, longitudinal, cohort study that enrolled approximately 100,000 women to refine the predictive ability of the Galleri® test to detect invasive cancers.
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The Circulating Cell-free Genome Atlas (CCGA) Study
A multicenter, prospective, case-control, observational, longitudinal study designed to identify the best performing assay and then determine whether genome-wide cfDNA methylation sequencing in combination with machine learning could distinguish cancer from non-cancer and localize a signal shared by a large number of cancers.
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PATHFINDER Study
A prospective, interventional, return-of-results, multi-center study to assess the implementation of an earlier version of the Galleri® multi-cancer early detection (MCED) test in a clinical setting. Later, blood samples were reanalyzed with the current version of Galleri.
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Publications
Transparency and sharing our learnings with the broader clinical and scientific community is of the utmost importance. This is why we publish manuscripts in a variety of peer-reviewed journals and present at medical conferences around the world to communicate our findings.
GRAIL is committed to helping fund innovative and impactful education to meet the needs of practicing healthcare professionals and the communities of care that they manage within our areas of interest.
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Externally sponsored research
GRAIL encourages the submission of scientifically sound and innovative research proposals.