An observational study of patients who have been administered the Galleri® test.

REFLECTION is a multi-center, prospective, non-interventional, cohort study that will enroll approximately 17,000 individuals who have opted to be screened with Galleri®, a blood-based, multi-cancer early detection (MCED) test in routine clinical settings. The purpose of the study is to understand the real-world experience of Galleri in clinical settings.

Patients who have been prescribed the Galleri test as part of medical care by their healthcare provider will have the opportunity to consent for participation into this data collection study.

The study will enroll participants from participating integrated delivery networks and other health systems in North America. Participants will be actively followed for 12 months from the time of enrollment through data capture from electronic health records and periodic self-report questionnaires. Participants may also be passively followed through linkages to cancer registries and other administrative health databases.